The Salisbury Seventh-Day Adventist Church began in Salisbury, North Carolina on August 30th, 1902 as a result of the second annual Session of the Carolina Conference of Seventh-Day Adventists, which was held in Salisbury from August 30th through September 7th, 1902. During the day, session time was spent in business meetings, where reports were given of the past year, plans were made for the coming year, and officers were selected to serve for the next year. In the evening sessions, however, attendees met for Bible study. These evening sessions were open to the public. Historical reports indicate that a large number of citizens from Salisbury came to participate.

Upon the conclusion of the conference session, local members followed New Testament direction and established “home churches”. One of the best remembered homes, where then members met, was that of Mrs. Myrties Dalrymple on South Church Street. As the number of members increased, they sought larger homes in which to meet. But over time, they ran out of homes that would accommodate the growing number of worshippers. Therefore, the next move was to rent an empty store building on North Main Street across from the old trolley barn.